PCU can refer to:
Pre-Commissioning Unit, a description used for United States Navy vessels prior to commission and the personnel units assigned to them
PCU (film), a 1994 film lampooning political correctness on college campuses, set at the fictitious Port Chester University
Communist Party of Uruguay (Partido Comunista del Uruguay)
Communist Unification Party (Partido Comunista de Unificación), a political party in Spain
Pacific Coast University, a law school in Long Beach, California
Packet Control Unit, part of the Base Station Subsystem in a GSM network
Passenger Car Unit or passenger car equivalent, a metric used in transportation engineering
Patelco Credit Union, a credit union in California
Philippine Christian University in Manila, Philippines
Portage Credit Union Centre, an ice hockey and recreational complex in Portage la Prairie, Manitoba
Progressive care unit, an intermediate coronary care unit
PCU, a former NYSE ticker symbol for Southern Copper Corporation
Poplarville-Pearl River County Airport, by IATA airport code
Photo conductor unit, fuser drum unit used in laser printers