Opening Night may refer to:
Opening Night (1977 film), a 1977 drama film written and directed by John Cassavetes
Opening Night (2016 film)
Opening Night (album), a big band jazz recording of the Thad Jones / Mel Lewis Jazz Orchestra
Opening Night (novel), a detective novel by Ngaio Marsh
Opening Night (1970s TV series), a 1974-75 Canadian television series
"Opening Night" (Curb Your Enthusiasm)
"Opening Night" (Parenthood (2010 TV series))
Opening Night (2013 film), horror short film starring Tuesday Knight
Opening Night (video game), a 1995 edutainment computer game developed and published by MECC
